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Relationship between non-invasive haemodynamic responses and cardiopulmonary exercise testing in patients with

Milena Pelosi Rizk Sperling1,2, Flávia Cristina Rossi Caruso2, Renata Gonçalves Mendes2

  • 1Programa de Pós-graduação Interunidades Bioengenharia (EESC/FMRP/IQSC), Universidade de São Paulo, USP, São Carlos, SC, Brasil.

Clinical Physiology and Functional Imaging
|October 14, 2014
PubMed

Insights

Impedance cardiography (IC) measures are linked to some cardiopulmonary exercise testing (CPX) metrics in coronary artery disease (CAD) patients. This study explored the relationship between IC and CPX during exertion in CAD.

Area of Science:

  • Cardiology
  • Physiology
  • Medical Technology

Background:

  • Non-invasive hemodynamic assessment using impedance cardiography (IC) is valuable for monitoring cardiac function in coronary artery disease (CAD).
  • Current IC measurements are often limited to rest, while symptoms in CAD patients can manifest during exertion.
  • The relationship between exertion-based IC and cardiopulmonary exercise testing (CPX) in CAD is not well understood.

Purpose of the Study:

  • To investigate the association between impedance cardiography (IC) during exertion and established cardiopulmonary exercise testing (CPX) measures in patients with coronary artery disease (CAD).

Main Methods:

  • Nineteen male patients with CAD underwent simultaneous IC and CPX measurements using a cycle ergometer.
  • Key parameters measured included cardiac output (CO), stroke volume (SV), peak oxygen consumption (VO2), and oxygen uptake efficiency slope (OUES).

Main Results:

  • Peak oxygen consumption (VO2) showed a significant correlation with cardiac output (CO).
  • Peak oxygen pulse was associated with stroke volume (SV).
  • Oxygen uptake efficiency slope (OUES) correlated with both resting and peak stroke volume (SV).

Conclusions:

  • Impedance cardiography (IC) indices demonstrate associations with specific, but not all, cardiopulmonary exercise testing (CPX) parameters in patients with stable coronary artery disease (CAD).
Abstract

Keywords:
cardiac diseasecardiac outputcardiopulmonary exercise testingimpedance cardiographyoxygen uptakeoxygen uptake efficiency slopestroke volume

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