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Motor Speech Disorders Associated with Primary Progressive Aphasia
Joseph R Duffy1, Edythe A Strand1, Keith A Josephs1
1Dept. of Neurology, Mayo Clinic, 200 First Street SW, Rochester, MN, U.S.A.
Motor speech disorders frequently accompany primary progressive aphasia (PPA) and related conditions. Recognizing these speech issues aids in diagnosing, managing, and understanding the pathology of PPA and its variants.
Area of Science:
- Neurology
- Speech-Language Pathology
Background:
- Primary progressive aphasia (PPA) can present with motor speech disorders.
- Understanding these disorders is crucial for PPA clinical management, localization, and pathology.
- Overlap syndromes include progressive supranuclear palsy, corticobasal syndrome, and motor neuron disease.
Purpose of the Study:
- To review motor speech disorders associated with PPA and its variants.
- To examine motor speech disorders in overlap syndromes and primary progressive apraxia of speech.
Main Methods:
- Literature review of motor speech disorders in PPA and related conditions.
Main Results:
- Motor speech disorders are common in PPA and its variants.
- Neurodegenerative apraxia of speech can occur with minimal or no aphasia.
- Recognition of motor speech disorders aids in PPA diagnosis and management.
Conclusions:
- Motor speech disorders are integral to PPA diagnosis and management.
- Identifying these disorders helps predict PPA variant localization and pathology.
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