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Related Experiment Video

Updated: Apr 22, 2026

Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer

Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer

Published on: February 12, 2017

[Pulmonary complications in chemotherapy].

A Becker¹, T Frauenfelder

¹Institut für Diagnostische und Interventionelle Radiologie, Universitätsspital Zürich, Rämistr. 100, CH-8091, Zürich, Schweiz.

|October 16, 2014

Summary

Chemotherapy can cause lung damage, posing diagnostic challenges due to nonspecific imaging findings. This review details lung changes from chemotherapy agents, aiding early detection and management of pulmonary complications.

Area of Science:

Pulmonary Medicine
Oncology
Radiology

Context:

Chemotherapeutic agents are widely used in cancer treatment.
These drugs can induce significant pulmonary and airway toxicity.
Early identification of these toxic effects via imaging is crucial but challenging.

Purpose:

To review the spectrum of lung and airway morphological changes induced by chemotherapeutic agents.
To correlate specific agents with their characteristic adverse pulmonary effects.
To assist clinicians in the early diagnosis of chemotherapy-induced lung injury.

Summary:

Chemotherapy-induced lung toxicity presents with diverse and often nonspecific imaging findings.
Morphological changes are categorized by anatomical location within the lungs and airways.

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Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer

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Commonly used chemotherapeutic agents and their associated pulmonary toxicities are enumerated.

Impact:

Improved recognition of chemotherapy-related lung disease.
Facilitation of earlier diagnosis and intervention for pulmonary complications.
Enhanced patient management and potentially reduced morbidity and mortality from lung toxicity.