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Keratoderma palmoplantaris striata.

M Casado, F Jimenez-Acosta, J Borbujo

    Clinical and Experimental Dermatology
    |May 1, 1989
    PubMed
    Summary
    This summary is machine-generated.

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    This study presents a patient with striate palmoplantar keratoderma, a rare genetic skin condition. The family showed a high incidence, and treatment with etretinate proved highly effective with minimal adverse effects.

    Area of Science:

    • Dermatology
    • Genetics
    • Pharmacology

    Background:

    • Keratoderma palmoplantaris striata is a rare inherited skin disorder.
    • Understanding its familial incidence and treatment options is crucial for patient management.

    Observation:

    • A case of keratoderma palmoplantaris striata is detailed.
    • A family tree revealed 36 affected relatives, indicating a significant familial incidence.
    • This represents the largest reported familial incidence in the reviewed literature.

    Findings:

    • The patient exhibited striate palmoplantar keratoderma.
    • Etretinate treatment resulted in an excellent response, effectively controlling skin lesions.
    • Minimal side-effects were observed during the treatment period.

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    Implications:

    • This case highlights the potential for high familial aggregation of keratoderma palmoplantaris striata.
    • Etretinate is a viable and effective therapeutic option for managing this condition.
    • Further research into the genetic basis and optimal treatment strategies for keratoderma palmoplantaris striata is warranted.