Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Hypersensitivity Reactions: Delayed Hypersensitivity Reactions

Hypersensitivity Reactions: Delayed Hypersensitivity Reactions

Delayed-Type Hypersensitivity (DTH), or Type IV hypersensitivity, is a cell-mediated immune response. It occurs when T cells, rather than antibodies, mediate a reaction to specific antigens. It is characterized by a delayed onset (1-2 days) and involves the recruitment of macrophages to the inflammation site.The initiation of a DTH response begins with the sensitization of T cells. During this phase, which lasts at least 1-2 weeks, antigen-specific T cells are activated, clonally expanded, and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

A Narrative Review of the Benefits of Board Games in Health.

Cureus·2025

Same author

Impact of Concomitant Proton Pump Inhibitor Use on the Efficacy of Immune Checkpoint Inhibitors Across Multiple Cancer Types.

Journal of the National Comprehensive Cancer Network : JNCCN·2025

Same author

Impact of Medical Student Involvement on Emergency Department Outcomes: A Tertiary Center Analysis.

The western journal of emergency medicine·2025

Same author

Open-lung ventilation versus no ventilation during cardiopulmonary bypass in an innovative animal model of heart transplantation.

Intensive care medicine experimental·2024

Same author

Look Past the Bleed! A Case of Non-Traumatic Thoracic Aortic Pseudoaneurysm Presenting as Haemoptysis.

European journal of case reports in internal medicine·2024

Same author

The Influence of Urbanization on the Patterns of Hepatocellular Carcinoma Mortality From 1999 to 2020.

Gastroenterology research·2024

Same journal

Empowering Residents in Community-based Internal Medicine Programs: A Structured Framework Integrating Simulation Labs, AI, and Gamification.

Journal of community hospital internal medicine perspectives·2026

Same journal

A Strategy for Surge Management: Senior Residents on the Admitting Frontlines.

Journal of community hospital internal medicine perspectives·2026

Same journal

A Comparison of Biological Therapies vs Traditional Immunosuppressant in the Management of Inflammatory Bowel Diseases: A Narrative Review.

Journal of community hospital internal medicine perspectives·2026

Same journal

The Shocking Case of a Bleeding Heart.

Journal of community hospital internal medicine perspectives·2026

Same journal

Short Term Outcomes and Resource Utilization in Patients Admitted for Infective Endocarditis Who Develop Pericardial Effusion: A Retrospective Cohort Study.

Journal of community hospital internal medicine perspectives·2026

Same journal

Remembrance of our Founder and Editor Emeritus.

Journal of community hospital internal medicine perspectives·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Apr 22, 2026

Stimulation of Stem Cell Niches and Tissue Regeneration in Mouse Skin by Switchable Protoporphyrin IX-Dependent Photogeneration of Reactive Oxygen Species In Situ

Stimulation of Stem Cell Niches and Tissue Regeneration in Mouse Skin by Switchable Protoporphyrin IX-Dependent Photogeneration of Reactive Oxygen Species In Situ

Published on: May 8, 2020

Lime-induced phytophotodermatitis.

Andrew Hankinson¹, Benjamin Lloyd², Richard Alweis²

¹Division of Dermatology, University of Vermont Medical Center, Burlington, VT, USA.

Journal of Community Hospital Internal Medicine Perspectives

|October 16, 2014

Summary

This summary is machine-generated.

Phytophotodermatitis, a skin reaction from plant compounds and sun exposure, can be mistaken for other conditions. Awareness is key for accurate diagnosis and treatment of this photosensitive dermatitis.

Keywords:

Rutaceae dermatitis lime photodermatitis phytodermatitis psoralen

More Related Videos

Quail Chorioallantoic Membrane - A Tool for Photodynamic Diagnosis and Therapy

Quail Chorioallantoic Membrane - A Tool for Photodynamic Diagnosis and Therapy

Published on: April 28, 2022

Isolating and Incorporating Light-Harvesting Antennas from Diatom Cyclotella Meneghiniana in Liposomes with Thylakoid Lipids

Isolating and Incorporating Light-Harvesting Antennas from Diatom Cyclotella Meneghiniana in Liposomes with Thylakoid Lipids

Published on: August 28, 2018

Related Experiment Videos

Last Updated: Apr 22, 2026

Stimulation of Stem Cell Niches and Tissue Regeneration in Mouse Skin by Switchable Protoporphyrin IX-Dependent Photogeneration of Reactive Oxygen Species In Situ

Stimulation of Stem Cell Niches and Tissue Regeneration in Mouse Skin by Switchable Protoporphyrin IX-Dependent Photogeneration of Reactive Oxygen Species In Situ

Published on: May 8, 2020

Quail Chorioallantoic Membrane - A Tool for Photodynamic Diagnosis and Therapy

Quail Chorioallantoic Membrane - A Tool for Photodynamic Diagnosis and Therapy

Published on: April 28, 2022

Isolating and Incorporating Light-Harvesting Antennas from Diatom Cyclotella Meneghiniana in Liposomes with Thylakoid Lipids

Isolating and Incorporating Light-Harvesting Antennas from Diatom Cyclotella Meneghiniana in Liposomes with Thylakoid Lipids

Published on: August 28, 2018

Area of Science:

Dermatology
Toxicology
Botany

Background:

Phytophotodermatitis is a skin inflammation triggered by contact with photosensitizing plant compounds followed by sun exposure.
Common culprits include citrus fruits, celery, and wild parsnip, which contain furocoumarins.
This condition can mimic other dermatological issues, leading to misdiagnosis.

Purpose of the Study:

To highlight a case of lime-induced phytophotodermatitis.
To emphasize the importance of physician awareness regarding phytophotodermatitis.
To differentiate phytophotodermatitis from other skin conditions.

Main Methods:

Case report presentation.
Review of literature on photosensitizing plant compounds.
Clinical observation and differential diagnosis.

Main Results:

The case illustrates a clear instance of phytophotodermatitis caused by lime exposure and subsequent sunlight.
Phytophotodermatitis shares clinical features with fungal infections, cellulitis, allergic contact dermatitis, and even child abuse.
Misdiagnosis can delay appropriate management.

Conclusions:

Physicians must consider phytophotodermatitis in patients with characteristic skin lesions after plant exposure and sun.
Early and accurate diagnosis prevents unnecessary treatments and potential harm.
Increased awareness can improve patient outcomes for this plant-induced photosensitive reaction.