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Molecular properties of the fungal plasma-membrane [H+]-ATPase
1Department of Human Genetics, Yale School of Medicine, New Haven, Connecticut 06510.
Journal of Bioenergetics and Biomembranes
|October 1, 1989
Abstract:
The fungal plasma membrane contains a proton-translocating ATPase that is closely related, both structurally and functionally, to the [Na+, K+]-, [H+, K+]-, and [Ca2+]-ATPases of animal cells, the plasma-membrane [H+]-ATPase of higher plants, and several bacterial cation-transporting ATPases. This review summarizes currently available information on the molecular genetics, protein structure, and reaction cycle of the fungal enzyme. Recent efforts to dissect structure-function relationships are also discussed.