Related Experiment Video
Updated: Apr 22, 2026

16:43
Visualization of Endoplasmic Reticulum Subdomains in Cultured Cells
Published on: February 18, 2014
12.8K
The endoplasmic reticulum: a dynamic and well-connected organelle
Chris Hawes1, Petra Kiviniemi, Verena Kriechbaumer
1Department of Biological and Medical Sciences, Oxford Brookes University, Oxford, OX3 0BP, UK.
Journal of Integrative Plant Biology
|October 17, 2014
Summary
The endoplasmic reticulum (ER) is a dynamic organelle crucial for the secretory pathway. This review explores its structure, dynamics, and role in transporting cellular components and viral particles.
Area of Science:
- Cell Biology
- Molecular Biology
- Organelle Structure and Function
Background:
- The endoplasmic reticulum (ER) is the initial compartment within the secretory pathway.
- It is a highly dynamic and pleomorphic network of membranes (tubules and cisternae).
- The ER performs diverse and essential cellular functions.
Purpose of the Study:
- To review the structure and dynamics of the endoplasmic reticulum.
- To examine the ER's relationship with adjacent organelles.
- To discuss the ER's function as a transport highway for cellular components and viral particles.
Main Methods:
- Literature review of endoplasmic reticulum research.
- Analysis of structural and dynamic properties of the ER.
- Examination of ER interactions with other organelles.
Main Results:
- The ER exhibits significant structural plasticity and dynamic behavior.
- The ER network facilitates the distribution of various cellular components.
- The ER serves as a conduit for the transport of structures, including viral particles.
Conclusions:
- The endoplasmic reticulum is a central and dynamic organelle in cellular transport.
- Understanding ER structure and dynamics is key to comprehending secretory pathway function.
- The ER's role as a transport highway has implications for both normal cellular processes and viral pathogenesis.
Related Concept Videos
Endoplasmic Reticulum
87.3K
The Endoplasmic Reticulum (ER) in eukaryotic cells is a substantial network of interconnected membranes with diverse functions, from calcium storage to biomolecule synthesis. A primary component of the endomembrane system, the ER manufactures phospholipids critical for membrane function throughout the cell. Additionally, the two distinct regions of the ER specialize in the manufacture of specific lipids and proteins.
87.3K
The Endoplasmic Reticulum
12.8K
The endoplasmic reticulum or ER makes up for more than half of the membranes in a cell and accounts for 10% of total cell volume. It is also the primary protein and lipid synthesis factory for most cell organelles, such as the Golgi apparatus, lysosomes, secretory vesicles, and the plasma membrane. Despite being the most extensive and functionally complex subcellular organelle, ER was the last to be discovered. After years of deliberation, Keith Porter and George Palade in the year 1954,...
12.8K
The Endoplasmic Reticulum
3.3K
3.3K
Golgi Apparatus
75.7K
As they leave the Endoplasmic Reticulum (ER), properly folded and assembled proteins are selectively packaged into vesicles. These vesicles are transported by microtubule-based motor proteins and fuse together to form vesicular tubular clusters, subsequently arriving at the Golgi apparatus, a eukaryotic endomembrane organelle that often has a distinctive ribbon-like appearance.
75.7K
Golgi Apparatus
16.0K
Properly folded and assembled proteins are selectively packaged into vesicles that exit the ER. Motor proteins transport these vesicles to the Golgi apparatus for adding modifications that make these proteins functional at their destination.
The Golgi apparatus is a eukaryotic organelle that has a distinctive ribbon-like appearance. It is a primary sorting and dispatch station for cargo arriving from the ER. Newly arriving vesicles enter the cis face of the Golgi, closest to the ER, and are...
The Golgi apparatus is a eukaryotic organelle that has a distinctive ribbon-like appearance. It is a primary sorting and dispatch station for cargo arriving from the ER. Newly arriving vesicles enter the cis face of the Golgi, closest to the ER, and are...
16.0K
Golgi Apparatus
4.6K
4.6K

