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Screening rectal swabs for carbapenemase genes
Anneke van der Zee1, Lieuwe Roorda2, Gerda Bosman2
1Maasstad Laboratory, Molecular Diagnostics Unit, Rotterdam, The Netherlands zeea@maasstadziekenhuis.nl.
Abstract:
In an outbreak setting, we screened 16,296 samples from 3,644 patients by PCR for the presence of blaOXA-48, blaVIM, blaIMP, blaNDM, and blaKPC. The blaOXA-48 gene was found in samples from 43 patients infected with 9 different species of Enterobacteriaceae. Five patients had Pseudomonas aeruginosa isolates containing blaVIM. The negative predictive value of screening was 100%, and the positive predictive value was 86%.
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