[New aspects of hypertension management in patients with chronic kidney disease]
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Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
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Revue Medicale Suisse
|October 18, 2014
Insights
Hypertension frequently affects chronic kidney disease (CKD) patients, worsening kidney function and increasing cardiovascular risks. This review examines hypertension management strategies for CKD patients not on renal replacement therapy.
Area of Science:
- Nephrology
- Cardiology
- Clinical Medicine
Context:
- Hypertension is a common comorbidity in patients diagnosed with chronic kidney disease (CKD).
- Uncontrolled blood pressure significantly accelerates CKD progression and elevates the risk of major cardiovascular events.
- Renal disease, whether primary or secondary, often underlies or exacerbates hypertension in this population.
Purpose:
- To comprehensively review current and emerging treatment strategies for managing hypertension specifically in patients with chronic kidney disease.
- To provide an evidence-based overview of therapeutic options for hypertensive CKD patients, excluding those on renal replacement therapy (dialysis or transplantation).
Summary:
- The paper synthesizes data on pharmacological and non-pharmacological interventions for blood pressure control in CKD.
- Key therapeutic classes, including ACE inhibitors, ARBs, diuretics, and calcium channel blockers, are discussed in the context of CKD.
- Emerging treatment modalities and personalized approaches are also considered.
Impact:
- This review aims to guide clinicians in optimizing antihypertensive therapy for CKD patients, thereby mitigating disease progression.
- Improved blood pressure management can lead to a reduced incidence of cardiovascular complications and a better prognosis for CKD patients.
- The findings support evidence-based practice in nephrology and internal medicine for managing this high-risk patient group.
Abstract:
Hypertension is a frequent finding in patients with chronic kidney disease. Whether primary or secondary to renal disease, hypertension remains an important risk factory for the progression of chronic kidney disease and the occurrence of cardiovascular events. The objective of this paper is to review different treatment strategies in hypertensive CKD patients, with the exclusion of patients with renal replacement therapy such as dialysis or renal transplantation.
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