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Raynaud's phenomenon (secondary).

Ariane Herrick1, Lindsay Muir

  • 1Centre for Musculoskeletal Research, Salford Royal NHS Foundation Trust, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.

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Summary
This summary is machine-generated.

This review examines surgical treatments for severe secondary Raynaud's phenomenon, focusing on interventions like botulinum toxin, sympathectomy, and arterial reconstruction for complicated cases.

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Area of Science:

  • Vascular Surgery
  • Rheumatology
  • Dermatology

Background:

  • Raynaud's phenomenon involves episodic vasospasm of peripheral vessels, often triggered by cold or stress.
  • It presents with characteristic digit color changes: white (ischemia), blue (deoxygenation), and red (reperfusion).
  • Secondary Raynaud's phenomenon, linked to conditions like systemic sclerosis, can lead to severe digital ulcerations.

Purpose of the Study:

  • To systematically review the effects of surgical interventions for complicated secondary Raynaud's phenomenon.
  • To evaluate the effectiveness and safety of various surgical procedures in managing severe cases.

Main Methods:

  • Systematic literature review up to March 2014, searching Medline, Embase, and The Cochrane Library.
  • Inclusion of two studies meeting predefined criteria.
  • GRADE evaluation of evidence quality for reviewed interventions.

Main Results:

  • Two studies were identified for inclusion in the systematic review.
  • A GRADE evaluation was performed to assess the quality of evidence for surgical interventions.
  • The review identified several surgical options for complicated secondary Raynaud's phenomenon.

Conclusions:

  • The review presents information on the effectiveness and safety of diverse interventions.
  • Surgical options discussed include botulinum toxin, debridement, sympathectomy, arterial reconstruction, and amputation.
  • These interventions aim to manage severe secondary Raynaud's phenomenon and its complications.