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Updated: Apr 21, 2026

Investigating Receptor-ligand Systems of the Cellulosome with AFM-based Single-molecule Force Spectroscopy
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Effects of cellular viscoelasticity in multiple-bond force spectroscopy

V K Gupta1

  • 1Department of Mechanical Engineering, University of Maryland Baltimore County, 1000 Hilltop Circle, Baltimore, MD, 21250, USA, vkg@umbc.edu.

Biomechanics and Modeling in Mechanobiology
|October 20, 2014
PubMed
Summary

Cellular features like viscoelasticity and fluid drag affect receptor-ligand bond rupture. This study shows cell viscoelasticity lowers rupture forces and increases bond lifetime for polymorphonuclear leukocytes (PMNs).

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