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Evaluating acne-related post-inflammatory hyperpigmentation is a challenge even amongst experts
Chee Leok Goh1, Flordeliz Abad-Casintahan, Steven K W Chow
1National Skin Centre, Singapore.
The Journal of Dermatology
|October 21, 2014
Summary
Diagnosing post-inflammatory hyperpigmentation (PIH) in acne patients shows significant variability among dermatologists, particularly in Asian populations. Clearer diagnostic criteria are needed for accurate skin assessment.
Area of Science:
- Dermatology
- Aesthetic Medicine
- Clinical Research
Background:
- Post-inflammatory hyperpigmentation (PIH) is a common and challenging sequela of acne, especially in Asian skin.
- Accurate clinical assessment and management of PIH are often difficult, leading to patient distress.
Purpose of the Study:
- To evaluate diagnostic concordance for PIH among dermatologists.
- To assess variability in PIH diagnosis in patients with active acne, scarring, and pigmentation issues.
Main Methods:
- Seven dermatologists reviewed 64 anonymous clinical photographs of acne patients.
- Raters assessed the presence and severity of PIH during a single session.
Main Results:
- Significant variability observed between dermatologists in diagnosing PIH, with an average difference of 24% in diagnoses.
- Marked variability in severity ratings, though most cases were assessed as mild.
- Diagnosis variability was highest when active acne was present, with some raters mistaking PIH for erythema.
Conclusions:
- The study highlights the need for standardized clinical criteria to improve the accuracy of PIH evaluation.
- Further research is advocated to refine diagnostic approaches for PIH, especially in diverse populations.

