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Updated: Apr 21, 2026

Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
Published on: November 4, 2025
Craniofacial morphology in patients with Angle Class II division 2 malocclusion
Dana Cristina Bratu1, Raluca Adriana Bălan, Camelia Alexandrina Szuhanek
1Department of Pedodontics and Orthodontics, Department of Dental Prostheses Technology, Faculty of Dental Medicine, "Victor Babes" University of Medicine and Pharmacy, Timisoara, Romania; raluca_balan22@yahoo.com, georgepopa86@yahoo.com.
This study on Angle Class II division 2 malocclusion found that during growth, patients exhibit retroclined incisors, obtuse interincisal angles, and a decreased lower face height. These cephalometric characteristics remain stable throughout development.
Area of Science:
- Orthodontics
- Dentofacial Orthopedics
- Craniofacial Growth
Background:
- Cephalometric analysis is crucial for diagnosing dento-skeletal anomalies.
- Understanding growth-related changes in malocclusions is essential for effective treatment planning.
Purpose of the Study:
- To evaluate skeletal and dental changes in growing patients with Angle Class II division 2 malocclusion.
- To compare cephalometric parameters across different age groups to assess anomaly progression.
Main Methods:
- Analysis of 25 lateral skull teleradiographs using cephX software.
- Categorization of patients into three age groups (6-8, 9-14, 15-18 years).
- Application of Björk-Jarabak and Tweed cephalometric analyses, including incisor-skeletal landmark relationships, with ANOVA and t-tests for statistical analysis.
Main Results:
- Accentuated retroclination of maxillary central incisors and a very obtuse interincisal angle.
- Decreased lower anterior face height and reduced mandibular body length in early growth.
- Lower gonial angle values and a stable hypodivergent skeletal pattern throughout the growth period.
Conclusions:
- Angle Class II division 2 malocclusion presents specific cephalometric characteristics during growth.
- The hypodivergent skeletal pattern and dental features remain relatively stable during the observed growth period.
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