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Related Concept Videos

Synthesis and Functions of Calcitonin00:51

Synthesis and Functions of Calcitonin

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Calcitonin, a vital polypeptide hormone, regulates calcium levels within body fluids. It is released by the parafollicular cells, also known as C cells, situated in the follicular epithelium of the thyroid gland. Calcitonin responds to fluctuations in blood calcium levels and the influence of gastrointestinal hormones like gastrin and cholecystokinin.
The exact mechanisms by which calcitonin operates in calcium homeostasis remain elusive, but its significance is evident in several vital...
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Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

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Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
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Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

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Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
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Acute Pancreatitis II: Clinical Manifestations and Management01:30

Acute Pancreatitis II: Clinical Manifestations and Management

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Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
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Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

Acute Kidney Injury IV: Diagnostic Studies and Prevention

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Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
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SBAR II: Application of SBAR01:14

SBAR II: Application of SBAR

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SBAR is an effective communication tool used by healthcare professionals to communicate patient information accurately. SBAR stands for Situation, Background, Assessment, and Recommendation. For a better understanding, an example is given below.
SBAR Report from a Nurse to a Health Care Provider
S: "Hello, Dr. Smith. This is Jane, RN, from the Med Surg unit. I am calling to tell you about Ms. White in Room 210, who is experiencing increased pain and redness at her incision site. Her recent...
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Related Experiment Video

Updated: Apr 21, 2026

Detection and Quantification of Calcitonin Gene-Related Peptide CGRP in Human Plasma Using a Modified Enzyme-Linked Immunosorbent Assay
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Detection and Quantification of Calcitonin Gene-Related Peptide CGRP in Human Plasma Using a Modified Enzyme-Linked Immunosorbent Assay

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Bedside procalcitonin and acute care.

Manpreet Singh1, Lakesh Anand1

  • 1Department of Anaesthesia and Intensive Care, Government Medical College and Hospital, Chandigarh, India.

International Journal of Critical Illness and Injury Science
|October 23, 2014
PubMed
Summary
This summary is machine-generated.

Procalcitonin (PCT) is a biomarker for bacterial infections. Point-of-care testing (POCT) of PCT enables rapid diagnosis and management of critical patients, especially in intensive care units.

Keywords:
Early detectionpoint of careprocalcitonin

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Area of Science:

  • Biochemistry
  • Clinical Diagnostics
  • Medical Laboratory Science

Background:

  • Procalcitonin (PCT) is a protein precursor normally degraded, but elevated in severe bacterial infections.
  • High PCT blood levels indicate serious infection, necessitating rapid diagnostic approaches.
  • Point-of-care testing (POCT) offers crucial, timely results in critical care settings.

Purpose of the Study:

  • To review the significance of Procalcitonin (PCT) in point-of-care testing (POCT) scenarios.
  • To highlight the utility of PCT POCT in diagnosing and managing critical conditions.
  • To emphasize the role of rapid PCT diagnostics in clinical decision-making.

Main Methods:

  • Literature review focusing on Procalcitonin (PCT) and its application in point-of-care testing (POCT).
  • Analysis of diagnostic significance of PCT levels in various clinical settings.
  • Evaluation of the impact of POCT on patient management.

Main Results:

  • Elevated PCT levels are indicative of severe bacterial infections and sepsis.
  • POCT enables swift determination of PCT concentrations at the patient's bedside.
  • Rapid PCT results facilitate timely therapeutic interventions in critical care.

Conclusions:

  • PCT is a valuable biomarker for bacterial infections, particularly when assessed via POCT.
  • Point-of-care testing of PCT significantly aids in the rapid diagnosis and management of sepsis.
  • Integrating PCT POCT into clinical practice improves patient outcomes in critical care environments.