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Updated: Apr 21, 2026

Low Molecular Weight Protein Enrichment on Mesoporous Silica Thin Films for Biomarker Discovery
Published on: April 17, 2012
Molecular scavengers as carriers of analytes for mass spectrometry identification
Marek Smoluch1, Michal Ceglowski, Joanna Kurczewska
1AGH University of Science and Technology , Department of Biochemistry and Neurobiology, Faculty of Materials Science and Ceramics, Al. Mickiewicza 30, 30-059 Krakow, Poland.
Abstract:
Storage and preconcentration of various molecules by molecular scavengers for thermal desorption and identification by mass spectrometry is presented. A dielectric barrier discharge ionization source combined with a heating element for the chemical characterization of amines and organic acids, initially trapped by molecular scavengers, is described. The developed technique can be applied for preconcentration of minute amounts of molecules in liquid and gaseous phases, as well as their transportation and thorough analysis. The method, operating at ambient pressure, can also be complementary to electron impact ionization, with no need for sample derivatization.
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