Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Antiphlogistics in periodontology.

H Cerná, B Fiala, K Han

    Acta Universitatis Palackianae Olomucensis Facultatis Medicae
    |January 1, 1989
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Semisynthesis of C17:0 isoforms of sulphatide and glucosylceramide using immobilised sphingolipid ceramide N-deacylase for application in analytical mass spectrometry.

    Rapid communications in mass spectrometry : RCM·2010
    Same author

    [Determination of the antioxidant activity of potential scavengers of nitric oxide].

    Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti·2005
    Same author

    [Ketotifen fumarate (Zaditen) eye drops in the treatment of seasonal allergic conjunctivitis].

    Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti·2004
    Same author

    [Topical H1 antihistaminics in the therapy of acute conjunctival allergic reactions].

    Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti·2004
    Same author

    [Allergodil eye drops in the treatment of allergic conjunctivitis].

    Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti·2002
    Same author

    Enzymes immobilized on magnetic carriers: efficient and selective system for protein modification.

    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences·2002

    Sanchelin gel effectively treats inflammatory periodontal disease by reducing inflammation. Topical application in pockets showed better results than intrapapillary administration.

    Area of Science:

    • Periodontology
    • Pharmacology
    • Biomedical Engineering

    Background:

    • Inflammatory periodontal disease poses a significant oral health challenge.
    • Sanguinarine and chelerythrine, components of Sanchelin, have demonstrated antimicrobial and anti-inflammatory properties.
    • Novel drug delivery systems are crucial for effective periodontal therapy.

    Purpose of the Study:

    • To evaluate the therapeutic efficacy of Sanchelin gel and solution in treating inflammatory periodontal disease.
    • To compare the effectiveness of Sanchelin administered via topical gel versus intrapapillary solution.
    • To assess the impact of Sanchelin on clinical periodontal parameters and histological changes.

    Main Methods:

    • A study involving 146 individuals with inflammatory periodontal disease.

    Related Experiment Videos

  • Application of 0.05% Sanchelin in a 4% hydrogel carboxymethylcellulose gel into periodontal pockets.
  • Administration of Sanchelin in aqueous solution via intrapapillary route, compared with 2% hydrocortisone.
  • Clinical evaluation using periodontal indexes and histological examination of papillae.

    • Main Results:

    • Sanchelin gel demonstrated significant effectiveness in treating inflammatory periodontal disease.
    • Intrapapillary administration of Sanchelin solution showed lesser therapeutic effect compared to the gel form.
    • Histological analysis supported the clinical findings regarding treatment efficacy.

    Conclusions:

    • Sanchelin gel is an effective therapeutic agent for inflammatory periodontal disease.
    • Topical application of Sanchelin gel is superior to intrapapillary administration for periodontal treatment.
    • Further research may explore optimized formulations and delivery methods for Sanchelin.