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Updated: Apr 21, 2026
Assessment of Ovarian Cancer Spheroid Attachment and Invasion of Mesothelial Cells in Real Time
Published on: May 20, 2014
Parameters for predicting granulosa cell tumor of the ovary: a single center retrospective comparative study
Huseyin Yesilyurt1, Aytekin Tokmak, Ali Irfan Guzel
1Obstetrics and Gynecology, Dr Zekai Tahir Burak Women's Health Education and Research Hospital, Ankara, Turkey
Background:
To evaluate factors for predicting the granulosa cell tumor of the ovary (GCTO) pre-operatively.
Materials And Methods:
This retrospective designed study was conducted on 34 women with GCTO as the study group and 76 women with benign ovarian cysts as the control group. Data were recorded from the hospital database and included age, body mass index (BMI), parity, serum estradiol (E2) levels, diameter of the mass, ultrasonographic features, serum CA125 level, risk of malignancy index (RMI), duration of menopause, postoperative histopathology result, and the neutrophil/lymphocyte ratio (NLR).
Results:
The demographic parameters showed no statistically significant difference between the groups. Preoperative diameter of the mass, CA125, duration of menopause, and neutrophil/lymphocyte ratio were significantly different between the groups. ROC curve analysis demonstrated that diameter of the mass, serum estradiol and Ca125 levels, RMI and NLR may be discriminative factors in predicting GCTO preoperatively.
Conclusions:
In conclusion, we think that a careful preoperative workshop including diameter of the mass, serum estradiol (E2) and Ca125 levels, RMI and NLR may predict GCTO and may prevent incomplete approaches.
