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Magnetic-, Acoustic-, and Optical-Triple-Responsive Microbubbles for Magnetic Hyperthermia and Pothotothermal Combination Cancer Therapy
Published on: May 22, 2020
Of microspheres and microbes: A double-hit strategy for cancer immunotherapy
Benjamin Brinkhoff1, Thomas C Wirth1
1Department of Gastroenterology, Hepatology and Endocrinology; Medical School Hannover; Hannover, Germany.
Abstract:
Efficient immunotherapy relies on the rapid generation of elevated amounts of cancer-specific T lymphocytes. We have recently demonstrated that both rapid and potent tumor-targeting immune responses can be induced with a heterologous prime-boost regimen consisting of poly-lactic co-glycolic acid (PLGA) microsphere-based immunization followed by Listeria monocytogenes infection.
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