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Paramyxoviruses for Tumor-targeted Immunomodulation: Design and Evaluation Ex Vivo
Published on: January 7, 2019
Prostate cancer: Important steps and considerations in the design of therapeutic vaccines
Stephanie Eb McArdle1, A Graham Pockley1, Glen R Gibson2
1The John van Geest Cancer Research Centre; Nottingham Trent University; Nottingham, UK.
Abstract:
Vaccine-based immunotherapy can increase the overall survival of patients with advanced prostate cancer. However, the efficacy of vaccine-elicited anticancer immune responses is heavily influenced by the physical, nutritional, and psychological status of the patient. Given their importance, these parameters should be carefully considered for the design of future clinical trials testing this immunotherapeutic paradigm in prostate cancer patients.
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