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Published on: June 1, 2019
Magnetic resonance imaging-guided occult breast lesion localization and simultaneous sentinel lymph node mapping
Marcos Fernando de Lima Docema, Paulo Aguirre Costa, Felipe Eduardo Martins de Andrade
1Discipline of Mastology, Escola Paulista de Medicina, Universidade Federal de São Paulo (UNIFESP), Rua Botucatu 740, Vila Clementino, CEP 04023-062, São Paulo, SP, Brazil. simone.elias3@gmail.com.
Radio-guided occult lesion localization is a feasible technique for mapping non-palpable breast lesions and identifying sentinel lymph nodes. This method proved simple, reproducible, and effective for diagnosis and metastasis detection.
Area of Science:
- Oncology
- Radiology
- Surgical Oncology
Background:
- Radio-guided occult lesion localization (ROLL) is established for diagnosing non-palpable breast lesions.
- This study evaluates the feasibility of pre-operative ROLL for suspect non-palpable breast lesions and sentinel lymph node identification.
Purpose of the Study:
- To determine the feasibility of pre-operative radio-guided occult lesion localization for suspect non-palpable breast lesions.
- To assess the utility of this technique in identifying sentinel lymph nodes for metastasis detection.
Main Methods:
- A retrospective descriptive study analyzed data from 25 patients with 34 suspect breast lesions.
- Pre-operative mapping utilized magnetic resonance imaging-guided radiopharmaceutical injection.
- Lesion resection was guided by a gamma probe, with confirmation of complete radioactive material removal.
Main Results:
- Malignancy was confirmed in 60% of patients (15/25), including various types of breast cancer.
- Sentinel lymph node resection in 10 patients revealed metastases in 3.
- No adverse side effects were reported with the magnetic resonance imaging-guided radiopharmaceutical injection.
Conclusions:
- Sentinel node occult lesion localization is a simple, reproducible, and effective alternative for mapping suspect breast lesions.
- It is a valuable method for identifying lymph node metastasis.
- This technique offers advantages over methods like mammotomy and hook-wire localization.
