[Clinical, epidemiological, and etiological studies of aseptic meningitis in adults]

Shinichi Takeshima1, Shuichiro Neshige, Takahiro Himeno

  • 1Department of Neurology, Brain Attack Center, Ota Memorial Hospital.

Insights

Aseptic meningitis epidemics in adults are primarily caused by enteroviruses, particularly echovirus types 9 and 6. These infections, often occurring in summer and autumn, generally have a favorable prognosis.

Area of Science:

  • Infectious Diseases
  • Neurology
  • Virology

Context:

  • Aseptic meningitis is a significant cause of neurological illness in adults.
  • Epidemic occurrences of aseptic meningitis have been observed, particularly during warmer months.
  • Enteroviruses are a common cause of viral meningitis.

Purpose:

  • To investigate the etiological agents and epidemiological patterns of aseptic meningitis in adults.
  • To identify the specific enteroviruses responsible for epidemic aseptic meningitis.
  • To compare clinical and laboratory findings between different enteroviral meningitis types.

Summary:

  • A 10-year study identified aseptic meningitis in 360 adults, with a small epidemic in summer/autumn 2012.
  • Enteroviruses, including echovirus types 9 and 6, were the primary cause of epidemic aseptic meningitis.
  • Sporadic cases of mumps, varicella-zoster, and herpes simplex virus meningitis were also noted.

Impact:

  • Highlights enteroviruses as the main etiological agents for adult aseptic meningitis epidemics.
  • Provides insights into the seasonal patterns and viral identification rates for aseptic meningitis.
  • Confirms the generally benign prognosis of enteroviral meningitis in adults.

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