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An Air-liquid Interface Bronchial Epithelial Model for Realistic, Repeated Inhalation Exposure to Airborne Particles for Toxicity Testing
Published on: May 13, 2020
[Research progress about the relationship between nanoparticles silicon dioxide and lung cancer]
Chun Dai1, Yunchao Huang1, Yongchun Zhou1
1Department of Cardio-Thoracic Surgery, the Third Affiliated Hospital of Kunming Medical University (Yunnan Province Tumor Hospital), Yunnan Key Laboratory of Lung Cancer Research, Kunming 650000, China.
Abstract:
Nano-silicon dioxide widely distributed in plastic, rubber, ceramics, paint, adhesives, and many other fields, and it is the product of coal combustion. A growing evidence shows that nano-silicon dioxide has certain correlation with respiratory system disease. In this paper, we synthesized existing researches of domestic and abroad, summarized the lung toxicity of nanoparticles. This article are reviewed from the physical and chemical properties of nanoparticles silicon dioxide, exposure conditions and environment, and the pathogenic mechanism of nano-silicon dioxide.

