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Updated: Apr 21, 2026

Analyzing Large Protein Complexes by Structural Mass Spectrometry
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Enhanced single molecule mass spectrometry via charged metallic clusters

Christopher E Angevine1, Amy E Chavis, Nuwan Kothalawala

  • 1Department of Physics, Virginia Commonwealth University , Richmond, Virginia 23284, United States.

Analytical Chemistry
|October 25, 2014
PubMed
Summary

Adding a gold nanoparticle cluster to nanopores significantly enhances the detection of molecules like polyethylene glycol (PEG). This method improves the accuracy and range of nanopore sensing for various charged analytes.

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