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[Risk factors for death in children with severe hand, foot and mouth disease]

Chun-Lan Song1, Yi-Bing Cheng, Dan Chen

  • 1Department of Intensive Care Unit II, Zhengzhou Children′s Hospital, Zhengzhou 450003, China. 13703829317@163.com.

Zhongguo Dang Dai Er Ke Za Zhi = Chinese Journal of Contemporary Pediatrics
|October 26, 2014
PubMed

Insights

Severe hand, foot, and mouth disease (HFMD) poses a significant risk. Key predictors of mortality in children include pulmonary hemorrhage, abnormal blood pressure, and elevated serum lactate levels.

Area of Science:

  • Pediatric infectious diseases
  • Critical care medicine
  • Epidemiology

Context:

  • Severe hand, foot, and mouth disease (HFMD) is a serious condition in children.
  • Identifying mortality predictors is crucial for timely intervention.

Purpose:

  • To determine independent risk factors for death in children with severe HFMD.
  • To analyze clinical and laboratory data for prognostic indicators.

Summary:

  • A study of 164 severe HFMD cases identified pulmonary hemorrhage, abnormal blood pressure, and elevated serum lactate as independent predictors of mortality.
  • Multivariate logistic regression analysis revealed significant differences in clinical signs and laboratory values between survivors and non-survivors.

Impact:

  • Findings aid in early risk stratification and management of severe HFMD cases.
  • Highlights critical indicators for clinicians to monitor in critically ill children with HFMD.
Abstract

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