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Progress in developing analytical and label-based dietary supplement databases at the NIH Office of Dietary
Johanna T Dwyer1, Mary Frances Picciano1, Joseph M Betz1
1Office of Dietary Supplements, National Institutes of Health, US Department of Health and Human Services (DHHS), Bethesda, MD, USA.
Summary
Accurate data on dietary supplement ingredients are lacking. The Office of Dietary Supplements (ODS) is developing databases, including the Dietary Supplement Ingredient Database (DSID), to analyze supplement content and improve intake estimations.
Area of Science:
- Nutrition Science
- Public Health
- Analytical Chemistry
Background:
- Limited analytical data exists for bioactive constituents in the 50% of US adults consuming dietary supplements.
- Existing databases lack comprehensive, chemically verified information on supplement composition.
- Variability in multivitamin-mineral supplement (MVM) composition and bioavailability necessitates accurate data.
Purpose of the Study:
- To describe initiatives by the Office of Dietary Supplements (ODS) to enhance dietary supplement database development.
- To improve the quantitative and qualitative estimation of dietary supplement contributions to total nutrient intake.
- To address the lack of analytical data on the bioactive constituents in widely consumed dietary supplements.
Main Methods:
- Developing the Dietary Supplement Ingredient Database (DSID) through chemical analysis, initially focusing on adult multivitamin-mineral supplements (MVMs).
- Collaborating with the United States Department of Agriculture for DSID development.
- Enhancing the National Health and Nutrition Examination Survey (NHANES) dietary supplement label database through collaboration with the National Center for Health Statistics.
- Exploring the feasibility of a comprehensive US dietary supplement label database.
Main Results:
- Analytical verification of MVMs is underway, addressing products with undefined compositions and unknown label value deviations.
- Development of a certified reference material for MVM analysis is in progress.
- Enhancements to NHANES database will improve dietary intake estimations.
- A new project is assessing the practicality of a complete US dietary supplement label database.
Conclusions:
- The DSID will enable more accurate estimations of nutrient contributions from dietary supplements.
- Improved databases will aid in evaluating the role of supplements in health and well-being.
- These ODS initiatives aim to provide essential, analytically substantiated data for researchers and consumers.
Keywords:
Analytical substantiationCertified reference materialsDSIDDSLD-USADietary supplement compositionDietary supplement ingredient databaseDietary supplement labelsDietary supplementsNHANESNHANES-DSLDStandard reference materials®More Related Videos
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