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Updated: Apr 21, 2026

Measuring Frailty in HIV-infected Individuals. Identification of Frail Patients is the First Step to Amelioration and Reversal of Frailty
Published on: July 24, 2013
Psychiatric Diagnoses among an HIV-Infected Outpatient Clinic Population
Enbal Shacham1, Nur F Önen2, Michael F Donovan3
1Department of Behavioral Sciences and Health Education, College for Public Health and Social Justice, Saint Louis University, St Louis, MO, USA eshacham@slu.edu.
Insights
Psychiatric and substance use disorders are common in people with HIV, impacting comprehensive care. Few links were found between these conditions and HIV disease status in this urban clinic population.
Area of Science:
- Public Health
- Psychiatry
- Infectious Diseases
Background:
- Longer lifespans for individuals with HIV infection necessitate integrated psychiatric care.
- Psychiatric disorders are increasingly recognized as a critical component of comprehensive HIV management.
- Understanding the prevalence and associations of psychiatric conditions is vital for improving patient outcomes.
Purpose of the Study:
- To assess the prevalence of current psychiatric disorders in an outpatient HIV clinic population.
- To investigate associations between psychiatric disorders and HIV disease status, including viral load and therapy.
- To identify common substance use disorders co-occurring with psychiatric conditions in this demographic.
Main Methods:
- Recruitment of participants from an urban outpatient HIV clinic.
- Conducting interviews with 201 participants to assess psychiatric diagnoses and substance use.
- Analyzing data for associations between psychiatric disorders, substance use, and HIV disease markers (e.g., viral suppression).
Main Results:
- Major depressive disorder, generalized anxiety, and agoraphobia were prevalent psychiatric diagnoses.
- Alcohol and cocaine/crack abuse/dependence were common substance use disorders.
- Agoraphobia was uniquely associated with unsuppressed viral load; generalized anxiety was linked to less HIV therapy receipt.
Conclusions:
- Psychiatric and substance use disorders are highly prevalent in urban HIV clinic populations.
- Limited associations were found between most psychiatric diagnoses and HIV disease status.
- Integrated care models are essential for addressing the mental health needs of individuals living with HIV.
Abstract:
As individuals with HIV infection are living longer, the management of psychiatric disorders has increasingly been incorporated into comprehensive care. Individuals were recruited from an outpatient HIV clinic to assess the prevalence and related associations of current psychiatric disorders and biomarkers. Of the 201 participants who completed the interviews, the median age was 43.5 years, and the majority was male and African American. Most were receiving HIV therapy and 78% of those had achieved virologic suppression. Prevalent psychiatric diagnoses included major depressive disorder, generalized anxiety, and agoraphobia. Alcohol and cocaine/crack abuse and dependence were common substance use disorders. Current receipt of HIV therapy was less common among those diagnosed with generalized anxiety disorder. Agoraphobia was the only disorder associated with unsuppressed viral load. Psychiatric and substance use disorders are highly prevalent among an urban HIV clinic population, although we identified few associations between psychiatric diagnoses and HIV diseases status.
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