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Toxic phytochemicals and their potential risks for human cancer
1The Hormel Institute, University of Minnesota, Austin, Minnesota.
Cancer Prevention Research (Philadelphia, Pa.)
|October 29, 2014
Summary
Many plant-derived phytochemicals, while natural, can be harmful. Some commonly consumed plant compounds act as carcinogens or tumor promoters and should be avoided for health safety.
Area of Science:
- Plant science
- Toxicology
- Human health
Background:
- Humans have consumed plants for health benefits since antiquity.
- Phytochemicals are natural compounds in edible plants, often perceived as safe.
- Dietary intake of plant-derived compounds is widespread globally.
Purpose of the Study:
- To investigate the safety of commonly consumed plant-derived phytochemicals.
- To identify potential health risks associated with natural plant compounds.
- To raise awareness about the dual nature of phytochemicals in human diet.
Main Methods:
- Literature review of phytochemicals in common food plants.
- Analysis of toxicological data on natural plant compounds.
- Epidemiological data review on plant consumption and health outcomes.
Main Results:
- Phytochemicals exhibit diverse biological activities.
- Some naturally occurring plant compounds are identified as potential carcinogens.
- Certain commonly consumed plant constituents function as tumor promoters.
Conclusions:
- The assumption of universal safety for all plant-derived phytochemicals is incorrect.
- Risk assessment is crucial for plant compounds in the human diet.
- Dietary guidance should consider the potential adverse effects of specific phytochemicals.
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