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Updated: Apr 21, 2026
Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions
Published on: April 23, 2021
Executive testing predicts functional loss in subjects with white matter lesions
Felipe Kenji Sudo1, Gilberto Sousa Alves, Letice Ericeira-Valente
1a Center for Subjects with Alzheimer's Disease and Related Disorders, Institute of Psychiatry, Federal University of Rio de Janeiro (CDA/IPUB/UFRJ) , Rio de Janeiro , Brazil.
Abstract:
In order to assess ecological validity of executive function (EF) tests and the impact of EF dysfunction on functional status in elderly subjects with moderate and severe subcortical white matter hyperintensities (WMHs), we made a correlation analysis between EF scores and two measures of Instrumental Activities of Daily Living (IADL). Trail-making test and CLOX correlated with the ability to perform IADL in subjects with severe WMH. EF tests might present low ecological validity for those with WMH below severe stage.
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