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First report of the ceftazidimase CTX-M-19 in South America
V García-Fulgueiras1, I Bado1, N F Cordeiro1
1Depto. de Bacteriología y Virología, Instituto de Higiene, Facultad de Medicina, Universidad de la República Montevideo, Uruguay.
Abstract:
We report the first detection of bla CTX-M-19 in South America, harboured in an Escherichia coli isolate obtained from a urine sample; such an isolate belonged to phylogenetic group A, ST603, and showed a ceftazidimase profile. bla CTX-M-19 was encoded in an approximately 100 kb IncI1/IncF conjugative plasmid, featuring pndAC and hok/sok addiction systems; the β-lactamase gene was flanked upstream by three tandem-like transposons (IS26, IS10 and ISEcp1), inserted one inside the other, and downstream by IS903.
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