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Updated: Apr 21, 2026
Quantification of Metal Leaching in Immobilized Metal Affinity Chromatography
Published on: January 17, 2020
Oligopeptide-heavy metal interaction monitoring by hybrid gold nanoparticle based assay
Jane Politi1, Jolanda Spadavecchia, Mario Iodice
1Institute for Microelectronics and Microsystems, Unit of Naples-National Research Council, Via P. Castellino 111, 80127, Italy.
Abstract:
Phytochelatins are small peptides that can be found in several organisms, which use these oligopeptides to handle heavy metal elements. Here, we report a method for monitoring interactions between lead(ii) ions in aqueous solutions and phytochelatin 6 oligopeptide bioconjugated onto pegylated gold nanorods (PEG-AuNrs). This study is the first step towards a high sensitive label free optical biosensor to quantify heavy metal pollution in water.
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