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Related Experiment Video

Updated: Apr 21, 2026

Competitive Genomic Screens of Barcoded Yeast Libraries

Competitive Genomic Screens of Barcoded Yeast Libraries

Published on: August 11, 2011

ArrayExpress update--simplifying data submissions.

Nikolay Kolesnikov¹, Emma Hastings¹, Maria Keays¹

¹European Molecular Biology Laboratory, European Bioinformatics Institute, EMBL-EBI, Wellcome Trust Genome Campus, Hinxton, CB10 1SD, UK.

Nucleic Acids Research

|November 2, 2014

Summary

This summary is machine-generated.

The ArrayExpress functional genomics database stores over 1.5 million assays from sequencing and microarray studies. A new submission tool, Annotare, has significantly reduced data submission times.

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Area of Science:

Bioinformatics
Genomics
Data Archiving

Background:

ArrayExpress is a major international functional genomics database at EMBL-EBI.
It serves as a repository for data supporting peer-reviewed publications.
The database houses over 7000 sequencing and 42,000 array-based studies.

Purpose of the Study:

To describe the current status and recent developments of the ArrayExpress database.
To highlight improvements in data submission processes and future directions.
To emphasize the importance of ArrayExpress as a resource for functional genomics data.

Main Methods:

Data are stored in the MAGE-TAB format for standardized analysis.
A new data submission tool, Annotare, has been developed and implemented.
Ongoing development focuses on data flow automation and multi-omics data integration.

Main Results:

ArrayExpress contains over 1.5 million assays from diverse functional genomics studies.
Sequencing-based submissions have doubled in the last 18 months.
The Annotare tool has reduced average submission time by nearly threefold.

Conclusions:

ArrayExpress is a stable, highly accessed resource for functional genomics data.
The implementation of Annotare streamlines the data submission process.
Future efforts will enhance data integration and automation for multi-omics representation.