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Hyperandrogenism produced by ovarian tumors in women at different life stages
Objective:
to evaluate the different presentations of hyperandrogenism produced by ovarian tumors in women at different life stages
Design:
case report.
Setting:
academic institutions.
Patient(S):
3 patients at different life stages, with increased androgen levels.
Intervention(S):
review of hospital records.
Main Outcome Measure(S):
clinical and biochemical features, treatment and follow-up.
Result(S):
a 10 year-old girl with Leydig cell tumor presented with hyperandrogenemia, virilization and changes in social behavior. Another patient, at reproductive age, with a tumor>10 cm, presented with signs of virilization and abdominal mass, whose pathologic analysis disclosed a carcinoid tumor of the ovary associated with stromal hyperplasia. The third patient was a postmenopausal woman with severe alopecia, who presented a steroid cell tumor, rare at that age.
Conclusion(S):
the evaluation of women with signs and symptoms of virilization should include a detailed clinical record, thorough physical examination and an appropriate hormonal dosage, especially when images are inconclusive.
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