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Related Concept Videos

Menopause01:28

Menopause

140
Menopause, a natural biological process marking the end of a woman's fertility, typically occurs between the fifth and sixth decade of life. This phase is characterized by the exhaustion of the ovarian follicle pool, leading to less responsive ovaries despite the high levels of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). The consequential decrease in estrogen production results in symptoms like hot flashes, heavy sweating, headaches, hair loss, muscle pains, vaginal...
140
Disorders of the Male Reproductive System01:20

Disorders of the Male Reproductive System

337
Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
337

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Updated: Jun 7, 2025

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Hyperandrogenism after menopause: diagnostic evaluation.

Carolina Fux-Otta1,2, Diana Torre2,3, Peter Chedraui1,4

  • 1Departamento de Endocrinología y Diabetes, Hospital Universitario de Maternidad y Neonatología, Facultad de Ciencias Médicas, Universidad Nacional de Córdoba, Córdoba, Argentina.

Climacteric : the Journal of the International Menopause Society
|November 14, 2024
PubMed
Summary

Postmenopausal hyperandrogenism, linked to cardiovascular risks, requires careful clinical and biochemical evaluation. Guidelines aid physicians in diagnosing and managing this condition, improving patient outcomes.

Keywords:
Hyperandrogenismdiagnosishirsutismmenopausevirilization

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Area of Science:

  • Endocrinology
  • Gynecology
  • Cardiology

Background:

  • Postmenopausal hyperandrogenism stems from imbalanced ovarian steroid secretion and decreased sex hormone-binding globulin.
  • Elevated androgens increase risks for cardiovascular events, gynecological neoplasms, and affect emotional well-being.

Purpose of the Study:

  • To provide clinical guidelines for evaluating postmenopausal hyperandrogenism.
  • To optimize therapeutic outcomes for affected women.

Main Methods:

  • Thorough medical history is crucial for diagnosis.
  • Biochemical evaluation includes determining total testosterone levels.
  • Imaging studies are used when diagnostic uncertainty arises.

Main Results:

  • Facial hirsutism and hair loss are common presentations.
  • Abrupt, severe signs with virilization and male-range testosterone necessitate ruling out tumors.
  • Reliable testosterone assays and imaging aid differential diagnosis.

Conclusions:

  • Accurate clinical and biochemical assessment is vital for managing postmenopausal hyperandrogenism.
  • Early identification and appropriate management can mitigate associated health risks.