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Updated: Apr 21, 2026

Generation of Integration-free Human Induced Pluripotent Stem Cells Using Hair-derived Keratinocytes
Published on: August 20, 2015
Laser-assisted generation of human induced pluripotent stem cells
Yang Liu1, Dongmei Wu, Donglin Lao
1Stem Cell Research Center and Core Facility, Sanford-Burnham Medical Research Institute, La Jolla, California.
Abstract:
This unit describes a procedure for generating human induced pluripotent stem cells (hiPSCs) using the Laser-Enabled Analysis and Processing (LEAP®) system, which combines high-throughput cell imaging with laser-mediated cell manipulation. Use of this system should not only improve the quality and uniformity of hiPSCs produced, but ultimately enable a more rapid, efficient, high-throughput, and automated production process.
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