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Area of Science:

  • Medical Physics
  • Radiological Dosimetry
  • Biomedical Engineering

Background:

  • Iodinated contrast media are widely used in medical imaging.
  • Understanding their impact on radiation dose is crucial for patient safety.
  • Previous studies have explored contrast agent effects on radiation interactions.

Purpose of the Study:

  • To investigate alterations in energy deposition patterns within tissue-equivalent phantoms after introducing iodinated contrast media.
  • To quantify the localized and total absorbed dose changes.

Main Methods:

  • Utilized Monte Carlo simulations (mcnp5) with validated analytical solutions.
  • Employed a phantom model with a central contrast sphere within a larger water sphere.
  • Simulated monoenergetic X-ray exposures (35-150 keV) at varying iodine concentrations (1-100 mg/ml).

Main Results:

  • Localized absorbed dose within the contrast sphere increased by up to a factor of 13.
  • At clinically relevant concentrations (10 mg/ml), localized doses doubled.
  • Total energy absorption increase was negligible (<1% to 6%), with dose reductions elsewhere in the phantom.

Conclusions:

  • Iodine addition significantly enhances localized absorbed doses, potentially by over tenfold.
  • Overall patient radiation dose increase is modest (<10%), primarily due to dose redistribution.
  • Contrast media alter energy deposition patterns locally rather than increasing total patient dose.