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Related Experiment Video

Updated: Apr 21, 2026

In Vivo Confocal Microscopy: A Standard Operating Procedure for the Detection of Demodex Mites at the Eyelid Margin

In Vivo Confocal Microscopy: A Standard Operating Procedure for the Detection of Demodex Mites at the Eyelid Margin

Published on: July 3, 2025

Blepharitis: always remember demodex.

Vipul Bhandari¹, Jagadeesh K Reddy¹

¹Department of Cornea and External Diseases, Sankara eye Centre, Coimbatore, Tamil Nadu, India.

Middle East African Journal of Ophthalmology

|November 6, 2014

Summary

This summary is machine-generated.

Demodex mites are highly prevalent in blepharitis patients, with anterior blepharitis (AB) and mixed blepharitis (MB) showing the highest infestation rates. Lid irritation and dandruff signal significant Demodex presence.

Keywords:

Blepharitis Demodex Eyelash Tea Tree Oil

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In Vivo Confocal Microscopy: A Standard Operating Procedure for the Detection of Demodex Mites at the Eyelid Margin

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Published on: July 3, 2025

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Induction of Ocular Surface Inflammation and Collection of Involved Tissues

Induction of Ocular Surface Inflammation and Collection of Involved Tissues

Published on: August 4, 2022

Area of Science:

Ophthalmology
Parasitology
Microbiology

Background:

Demodex mites are common ectoparasites found on human skin.
Blepharitis is a common inflammatory condition of the eyelids.
The role of Demodex infestation in various types of blepharitis requires further investigation.

Purpose of the Study:

To investigate the incidence and density of Demodex mite infestation on eyelashes.
To compare Demodex prevalence in patients with anterior blepharitis (AB), meibomian-gland dysfunction (MGD), and mixed blepharitis (MB) against a control group.

Main Methods:

Recruited 200 participants: 150 with diagnosed blepharitis (AB, MGD, MB) and 50 healthy controls.
Conducted standard eye examinations, gathered ocular symptomatology data, and performed digital photography of lid margins.
Collected eyelash samples for microscopic examination to quantify Demodex mites, analyzed using the Chi-square test.

Main Results:

Demodex infestation incidence was 90% in AB, 60% in MGD, and 90% in MB cases.
Control subjects showed a Demodex incidence of 18%.
Highest Demodex incidence and density were observed in patients with AB and MB.

Conclusions:

Demodex infestation is significantly more common in patients with AB and MB compared to controls.
Clinical signs like lid irritation and cylindrical dandruff are indicators of high-density Demodex infestation.
Clinicians should consider Demodex infestation in patients presenting with these signs and symptoms.