Endogenous Serratia marcescens endophthalmitis.

Area of Science:

• Ophthalmology
• Infectious Diseases
• Microbiology

Background:

• Endogenous endophthalmitis is a severe intraocular infection.
• Serratia marcescens is an opportunistic pathogen.
• Dental disease can be a source of systemic infections.

Observation:

• A human immunodeficiency virus (HIV)-negative patient with a history of intravenous drug use presented with acute vision loss and ocular inflammation.
• Ocular examination revealed hypopyon, vitritis, and elevated intraocular pressure.
• Computed tomography identified severe dental disease and gingival inflammation.

Findings:

• Intravitreal culture confirmed Serratia marcescens as the causative agent.
• Despite aggressive treatment with systemic and intravitreal antibiotics, the patient experienced rapid clinical deterioration.
• The affected eye was ultimately eviscerated.

Implications:

• This case highlights a rare etiology of endogenous endophthalmitis in an immunocompetent individual.
• Severe dental disease should be considered a potential source of Serratia marcescens endophthalmitis.
• Prompt dental intervention may be crucial in managing such cases.