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Updated: Apr 21, 2026
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In Vivo Multimodal Imaging and Analysis of Mouse Laser-Induced Choroidal Neovascularization Model
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Leaking choroidal nevus treated with focal laser photocoagulation
Darin R Goldman1, Alexander C Barnes, Robin A Vora
1*New England Eye Center at Tufts Medical Center, Boston, Massachusetts; †Ophthalmic Consultants of Boston, Boston, Massachusetts; and ‡Tuft University School of Medicine, Boston, Massachusetts.
Retinal Cases & Brief Reports
|November 6, 2014
Summary
Focal laser photocoagulation effectively treated a leaky choroidal nevus, resolving subretinal fluid and improving vision. This treatment for choroidal nevus complications showed sustained benefits over one year.
Area of Science:
- Ophthalmology
- Medical Retina
Background:
- Choroidal nevi are common benign melanocytic tumors of the posterior uvea.
- Leaky choroidal nevi can cause secondary subretinal fluid, leading to visual disturbances.
Observation:
- A 40-year-old male presented with decreased visual acuity due to subretinal fluid associated with a choroidal nevus.
- Diagnostic imaging included spectral domain optical coherence tomography (SD-OCT), fundus autofluorescence (FAF), and fundus photography.
Findings:
- Focal laser photocoagulation applied to the choroidal nevus surface successfully resolved the subretinal fluid within six weeks.
- One-year follow-up demonstrated sustained resolution of fluid, improved visual acuity, and no lesion growth.
Implications:
- Focal laser photocoagulation is a viable treatment option for symptomatic subretinal fluid secondary to choroidal nevi.
- SD-OCT, FAF, and fundus photography are valuable tools for monitoring treatment efficacy and disease progression.
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