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Updated: Apr 21, 2026
Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography
Published on: December 2, 2022
Paraneoplastic vitelliform retinopathy in a patient with treated choroidal melanoma
Steven L Williams1, H Richard McDonald, J Michael Jumper
1*Pacific Vision Foundation, California Pacific Medical Center, San Francisco, California; †West Coast Retina Medical Group, San Francisco, California; and ‡Department of Ophthalmology, Stanford University School of Medicine, Stanford, California.
Purpose:
To describe a peculiar case of paraneoplastic vitelliform maculopathy/retinopathy in a patient with treated choroidal melanoma.
Methods:
A case report of a 58-year-old woman with a history of treated choroidal melanoma 16 years before developing visual changes in the setting of metastatic choroidal melanoma.
Results:
We demonstrate bilateral, multifocal vitelliform subretinal lesions and focal, neurosensory retinal detachment associated with metastatic melanoma.
Conclusion:
Paraneoplastic vitelliform maculopathy/retinopathy should be considered in patients with or without a history of melanoma, who have unexplained serous, vitelliform retinal detachments, especially with atypical or absence of leakage on fluorescein angiography.
