Related Experiment Video

Updated: Apr 21, 2026

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
04:23

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease

Published on: April 28, 2019

6.4K

Outbreak of dengue Fever in central China, 2013

Xue Yong Huang1, Hong Xia Ma1, Hai Feng Wang1

  • 1Henan Center for Disease Control and Prevention, Zhengzhou 450016, Henan, China.

Biomedical and Environmental Sciences : BES
|November 7, 2014
PubMed

Insights

The first dengue fever outbreak in China's northern Henan province occurred in 2013, confirming dengue virus type 3. This event signals a concerning expansion of dengue fever's endemic range in China.

Area of Science:

  • Epidemiology
  • Infectious Diseases
  • Public Health

Background:

  • Dengue fever (DF) has historically been confined to southern China.
  • Northern temperate regions were previously considered less susceptible to DF outbreaks.

Purpose of the Study:

  • To report the first occurrence of a dengue fever outbreak in central China's Henan province.
  • To characterize the dengue virus type involved and assess local population exposure.

Main Methods:

  • Surveillance of suspected dengue fever cases.
  • Laboratory confirmation of dengue virus type 3 (DEN-3) infections.
  • Serological testing for dengue virus antibodies in local health personnel.

Main Results:

  • 106 suspected DF cases were reported, with 73 confirmed as DEN-3 infections.
  • 15.8% (62/392) of local health personnel exhibited positive DEN antibodies.
  • Henan province represents the northernmost region in China to report a DF outbreak.

Conclusions:

  • The 2013 Henan outbreak marks the northernmost occurrence of dengue fever in China.
  • This event indicates a significant geographical expansion of the dengue fever endemic range within China.
  • Increased vigilance and control measures are necessary in newly affected temperate regions.

More Related Videos

Mosquito-Associated Virus Isolation from Field-Collected Mosquitoes06:41

Mosquito-Associated Virus Isolation from Field-Collected Mosquitoes

Published on: August 31, 2022

2.5K
Evaluation of Zika Virus-specific T-cell Responses in Immunoprivileged Organs of Infected Ifnar1-/- Mice10:01

Evaluation of Zika Virus-specific T-cell Responses in Immunoprivileged Organs of Infected Ifnar1-/- Mice

Published on: October 17, 2018

11.2K

Related Concept Videos

Investigation of Disease Outbreaks01:23

Investigation of Disease Outbreaks

Multistate foodborne outbreaks pose significant public health risks and require meticulous investigation to identify sources and implement control measures. The Centers for Disease Control and Prevention (CDC) utilizes a dynamic seven-step process for these investigations, integrating data from laboratories, interviews, and environmental assessments to protect public health.Outbreak Detection: The detection of multistate outbreaks typically begins with PulseNet, the CDC's national laboratory...
69
Infectious Diseases and Their Occurrence01:28

Infectious Diseases and Their Occurrence

Infectious diseases appear in populations through various transmission patterns, influenced by pathogen characteristics, population immunity, environmental conditions, and social behavior. Understanding these patterns is essential for effective public health surveillance and intervention. These categories—sporadic, outbreak, epidemic, pandemic, and endemic—help frame the nature and scope of disease events.Sporadic diseases occur irregularly and infrequently, without a predictable...
78
Arboviral Encephalitis01:25

Arboviral Encephalitis

Arboviral encephalitis refers to brain inflammation caused by arthropod-borne viruses, particularly those transmitted through mosquito vectors. Among these, West Nile virus (WNV), a member of the Flaviviridae family, is a significant public health concern. WNV is an enveloped, positive-sense, single-stranded RNA virus. Human infection typically begins when an infected mosquito introduces the virus into the dermis during feeding. The primary transmission cycle involves birds as amplifying hosts...
52
Influenza01:27

Influenza

Influenza is an acute, highly communicable viral disease that affects the respiratory tract and is responsible for seasonal epidemics worldwide. Influenza A is the most prevalent type associated with widespread outbreaks and is subtyped based on two surface glycoproteins: hemagglutinin (H) and neuraminidase (N), as in H1N1. These glycoproteins are essential for viral infectivity, transmission, and immune recognition. Transmission occurs primarily through respiratory droplets and contaminated...
67
Cholera01:25

Cholera

Cholera is an acute gastrointestinal disease caused by the Gram-negative bacterium Vibrio cholerae. It is transmitted primarily via the fecal-oral route through the ingestion of contaminated water or food.Vibrio cholerae is a motile, Gram-negative bacterium of the family Vibrionaceae, primarily associated with waterborne outbreaks in areas with inadequate sanitation. Although over 200 serogroups of V. cholerae exist, only O1 and O139 are responsible for epidemic cholera. The O1 serogroup,...
130
Patterns of Fever01:26

Patterns of Fever

Before understanding the types and patterns of fever, it is essential to know its phases.
4.7K