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Related Concept Videos

Psychosurgery01:30

Psychosurgery

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Psychosurgery, the surgical alteration or permanent removal of brain tissue to alleviate severe psychological conditions, stands as one of the most radical and controversial treatments in the history of mental health care. Its development and application have evolved significantly, marked by dramatic shifts in scientific understanding and ethical perspectives.
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...
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Related Experiment Video

Updated: Apr 21, 2026

Stereotactic Radiosurgery for Gynecologic Cancer
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Stockholm radiosurgery developing 1968-1982.

Jeremy C Ganz

    Progress in Brain Research
    |November 8, 2014
    PubMed
    Summary
    This summary is machine-generated.

    Stockholm utilized gamma unit technology for 14 years, treating diverse conditions including vascular lesions and tumors. This early application predates computerized imaging, offering historical insights into radiation therapy.

    Keywords:
    AVManeurysmcraniopharyngiomafunctional indicationsmeningiomapituitary adenomavestibular schwannoma

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    Area of Science:

    • Neurosurgery
    • Radiation Oncology
    • Medical Physics

    Background:

    • Stockholm was the sole center using gamma unit technology for 14 years.
    • Initial design focused on functional diseases, later adapted for tumors and vascular lesions due to changing referral patterns.

    Observation:

    • The gamma unit underwent modifications, including the introduction of round collimators for improved efficacy.
    • Treatment encompassed a wide range of conditions, including vascular malformations, tumors, and functional neurological disorders.

    Findings:

    • A total of 762 patients were treated, with specific allocations: 209 for vascular indications, 342 for tumors, and 177 for functional disorders.
    • 34 diverse cases were also managed, highlighting the versatility of the gamma unit.
    • All treatments were performed prior to the advent of computerized imaging.

    Implications:

    • This study provides a historical overview of early gamma unit applications in clinical practice.
    • The findings underscore the adaptability of radiation technology to evolving medical needs and patient populations.
    • This work serves as a benchmark for understanding the evolution of image-guided radiation therapy.