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Antitachycardia pacemakers in congenital heart disease
Anna N Kamp1, Martin J LaPage, Gerald A Serwer
1Cardiology, The Heart Center, Nationwide Children's Hospital, Ohio State University, Columbus, Ohio, USA.
Insights
Antitachycardia pacing is effective for intraatrial reentrant tachycardia (IART) in congenital heart disease (CHD) patients with prior IART. Pacing may not benefit CHD patients without documented IART history.
Area of Science:
- Cardiology
- Electrophysiology
- Congenital Heart Disease
Background:
- Congenital heart disease (CHD) patients often develop rhythm abnormalities like intraatrial reentrant tachycardia (IART) post-surgery.
- Current treatments for IART in CHD include medication, ablation, and pacing, but evidence for pacing is limited.
Purpose of the Study:
- To evaluate the use and effectiveness of antitachycardia pacing (ATP) for treating IART in patients with CHD.
- To identify patient subgroups most likely to benefit from ATP.
Main Methods:
- Retrospective analysis of 80 antitachycardia pacemaker implants in 72 CHD patients between 2000 and 2010.
- Follow-up data analyzed for efficacy and complications, with a median follow-up of 2.8 years.
Main Results:
- Successful ATP was achieved in 36% of all patients and 57% of those with IART post-implant.
- Patients with two-ventricle repairs and prior documented IART showed higher success rates.
- Complication rates were 11% early and 5.6% late; 8% mortality was observed.
Conclusions:
- Antitachycardia pacing is a successful adjunctive therapy for IART in CHD patients, particularly those with a history of IART.
- Patients without prior documented IART are less likely to benefit from antitachycardia pacemaker implantation.
- Implantation should be considered for CHD patients with demonstrated IART, especially post-atrial switch procedures.
Background:
Many patients with congenital heart disease (CHD) acquire rhythm abnormalities related to their repair, most commonly intraatrial reentrant tachycardia (IART). Treatment of IART in CHD is often multifaceted, and may include medication, ablation, and pacing. Evidence regarding the use of antitachycardia pacing therapies is limited.
Objective:
The aim of the study is to define the use and efficacy of antitachycardia pacing in patients with CHD at a single center.
Results:
Eighty implants were performed on 72 patients between 2000 and 2010. Follow-up data of more than 3 months were available for 56 patients; median follow-up time was 2.8 years. Twenty (36%) patients received successful antitachycardia pacing at a median 1.3 years postimplant. For those patients with IART after implant, antitachycardia pacing was successful in 57%. Patients with two-ventricle repairs were more likely to have successful antitachycardia pacing than those with one-ventricle palliation (45% vs. 17%, P = .04). Patients with documented IART had more successful antitachycardia pacing than those with no documented atrial tachycardia prior to implant (46% vs. 7%, P = .006). Early complications of antitachycardia pacemaker implant occurred in six patients (11%); late complications after implant occurred in three patients (5.6%). Of the initial 72 patients implanted, there were six deaths (8%).
Conclusions:
Antitachycardia pacing therapies were successful in the majority of CHD patients who had IART after implant. Patients without documented atrial tachycardia prior to implant were unlikely to require or receive successful therapy from antitachycardia pacemaker. Those patients postatrial switch procedure who had documented IART prior to implant had the highest incidence of successful antitachycardia pacing therapies. Antitachycardia pacemaker implantation is an adjunct to the management of IART in CHD patients, but may not benefit patients who have not yet demonstrated IART.
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