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Updated: Apr 21, 2026

Development and Functionalization of Electrolyte-Gated Graphene Field-Effect Transistor for Biomarker Detection
Published on: February 1, 2022
Detection beyond Debye's length with an electrolyte-gated organic field-effect transistor
Gerardo Palazzo1, Donato De Tullio, Maria Magliulo
1Dipartimento di Chimica, Università degli Studi di Bari Aldo Moro, CSGI and INSTM, Via Orabona 4, 70126, Bari, Italy.
Abstract:
Electrolyte-gated organic field-effect transistors are successfully used as biosensors to detect binding events occurring at distances from the transistor electronic channel that are much larger than the Debye length in highly concentrated solutions. The sensing mechanism is mainly capacitive and is due to the formation of Donnan's equilibria within the protein layer, leading to an extra capacitance (CDON) in series to the gating system.
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