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A Label-free Technique for the Spatio-temporal Imaging of Single Cell Secretions

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Plasmonic biosensors.

¹Department of Biomedical Engineering, Duke University, Durham, NC, USA.

Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology

|November 8, 2014

Summary

This summary is machine-generated.

Plasmonic nanostructures offer unique optical properties for nanoscale sensing. This review highlights emerging localized surface plasmon resonance and coupled sensor technologies for advanced biosensing applications.

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Area of Science:

Optics
Nanotechnology
Biomedical Engineering

Background:

Plasmonics leverages unique optical properties of nanostructures for sensing.
Biosensing is a key application area for plasmonic technologies.
Traditional film-based surface plasmon resonance (SPR) sensors are widely used but have limitations.

Purpose of the Study:

To review the current landscape of plasmonic biosensors.
To emphasize emerging localized surface plasmon resonance (LSPR) and plasmonically coupled sensor technologies.
To discuss operating principles and practical considerations for developing plasmonic sensing platforms.

Main Methods:

Review of existing literature on plasmonic biosensors.
Analysis of operating principles for various plasmonic sensing techniques.
Evaluation of practical considerations for sensor development.

Main Results:

Film-based SPR sensors are the established standard.
Localized surface plasmon resonance (LSPR) sensors offer significant potential.
Plasmonically coupled sensors represent a developing and promising technology.

Conclusions:

Emerging LSPR and coupled plasmonic sensors may surpass current film-based SPR technology.
Understanding operating principles and practicalities is crucial for advancing plasmonic biosensing.
Plasmonics continues to be a rapidly evolving field with high potential in biosensing.