Related Experiment Video
Updated: Apr 21, 2026

Evaluation of Host-Pathogen Responses and Vaccine Efficacy in Mice
Published on: February 22, 2019
Improving Immunizations in Children: A Clinical Break-even Analysis.
Kyle Bradford Jones1, Chad Spain2, Hannah Wright3
1Department of Family and Preventive Medicine, University of Utah, Salt Lake City, Utah, USA Kyle.jones@hsc.utah.edu.
Improving childhood immunizations is crucial. A quality improvement project in Utah family medicine clinics significantly boosted vaccination rates in children under 3 through reduced missed opportunities and targeted outreach, proving cost-effective.
Area of Science:
- Public Health
- Pediatrics
- Family Medicine
Background:
- Immunization is a critical public health objective.
- This study details a quality improvement initiative in urban family medicine residency clinics.
- The project aimed to enhance immunization rates for children under three years old.
Purpose of the Study:
- To implement and evaluate a resident-led quality improvement project to increase childhood immunization rates.
- To assess the cost-effectiveness of the intervention through a break-even analysis.
Main Methods:
- Daily distribution of immunization records to provider-medical assistant teams to minimize missed opportunities.
- An outreach strategy involving letters and telephone calls for children under three who were behind on vaccinations.
- Monitoring immunization rates at three months post-intervention and conducting a financial break-even analysis.
Main Results:
- Immunization rates increased significantly from baseline (75.1% and 79.6%) to 92.1% and 89.6% at the two clinics within three months.
- The intervention demonstrated a positive financial return, with an average revenue of $81.57 per immunization.
- The financial break-even point for the outreach intervention was determined to be 36 administered immunizations.
Conclusions:
- A combined approach of reducing in-clinic missed immunization opportunities and implementing patient outreach effectively improved vaccination rates in young children.
- The intervention proved financially beneficial, generating positive revenue for the family medicine residency clinics.
- This quality improvement model offers a sustainable strategy for enhancing pediatric immunization coverage in primary care settings.
Related Concept Videos
Vaccinations
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Drug Dosing: Infants and Children
Pharmacokinetics in Pediatric Patients: Drug Excretion
Pharmacokinetics in Pediatric Patients: Drug Distribution
Clinical Trials
There are four phases in a clinical trial. A phase one...

