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Using the Pragmatic-Explanatory Continuum Indicator Summary (PRECIS) model in clinical research: Application to
1From the Department of Family and Community Medicine, University of Kentucky School of Medicine, Lexington (WGE); and the Department of Health Sciences, Indiana University School of Health and Rehabilitation Sciences, Indianapolis (NM). welder@uky.edu.
Journal of the American Board of Family Medicine : JABFM
|November 9, 2014
Summary
The Pragmatic-Explanatory Continuum Indicator Summary (PRECIS) model helps assess clinical trial design. Applying PRECIS revealed a pilot study was less pragmatic than anticipated, guiding future improvements for real-world applicability.
Area of Science:
- Clinical research methodology
- Health services research
- Trial design and evaluation
Background:
- Pragmatic clinical trials (PCTs) are vital for real-world intervention evaluation.
- The Pragmatic-Explanatory Continuum Indicator Summary (PRECIS) model aids in assessing trial generalizability and applicability.
- A pilot study on complementary therapies for chronic low back pain required pragmatic feature characterization.
Purpose of the Study:
- Introduce clinical researchers to the PRECIS model.
- Demonstrate the application of the PRECIS model to refine a practice-based research network study.
- Characterize the pragmatic features of a pilot study to inform future design decisions.
Main Methods:
- An exercise using an audience response system and a Works in Progress presentation was designed.
- Experienced researchers at the University of Kentucky participated in the exercise.
- Study methodologies were examined against parameters suggested by the PRECIS model.
Main Results:
- The exercise was smooth and engaging for participants.
- The pilot study received an overall PRECIS score of 30.17 (out of 48), indicating a moderate level of pragmatism.
- Component scores and a polar chart differentiated the study's design pragmatism across various components.
Conclusions:
- The pilot study was less pragmatic than initially expected.
- PRECIS model application identified necessary refinements for future study design and generalizability.
- The PRECIS model offers clarity and transparency for evaluating proposed or existing clinical studies.
Keywords:
Chronic DiseasePractice-based ResearchPragmatic Clinical TrialsQuality of LifeQuantitative EvaluationMore Related Videos
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