Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Lactation is Associated with Accelerated Postpartum Pelvic Floor Muscle Recovery in a Pregnant Simulated Birth Injury Model.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026

Same author

Impact of health insurance coverage on dentition status prior to hematopoietic cell transplant: A 10-year single-institution observational study.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer·2026

Same author

Feasibility of Non-Sedate Magnetic Resonance Imaging for Children with Cerebral Palsy: Tolerance and Structural Analysis Considerations.

Children (Basel, Switzerland)·2026

Same author

Immunotherapy in Synchronous Gastric and Colonic Deficient Mismatch Repair Malignancies in a Case Series of Patients With Lynch Syndrome.

JCO precision oncology·2026

Same author

Spontaneous healing of mandibular fracture due to osteoradionecrosis.

Oral oncology reports·2026

Same author

Oral manifestation associated with avelumab.

Oral oncology reports·2026

Same journal

Hypoxia and Parkinson's Disease: A Dangerous Oversimplification Based on a Subpar Mouse Model.

Nano LIFE·2025

Same journal

Intratumoral Photosensitizer Delivery and Photodynamic Therapy.

Nano LIFE·2021

Same journal

REVERSAL OF FIBRONECTIN-INDUCED HIPPOCAMPAL DEGENERATION WITH ENCAPSULATED MESENCHYMAL STROMAL CELLS.

Nano LIFE·2018

Same journal

Prostaglandin E<sub>2</sub> Produced by Alginate-Encapsulated Mesenchymal Stromal Cells Modulates the Astrocyte Inflammatory Response.

Nano LIFE·2018

Same journal

PRO-RESOLUTION POTENCY OF RESOLVINS D1, D2 AND E1 ON NEUTROPHIL MIGRATION AND IN DERMAL WOUND HEALING.

Nano LIFE·2018

Same journal

Sizes and Sufficient Quantities of MSC Microspheres for Intrathecal Injection to Modulate Inflammation in Spinal Cord Injury.

Nano LIFE·2018

See all related articles

Search research articles

Related Experiment Video

Updated: Apr 21, 2026

Cell Patterning on Photolithographically Defined Parylene-C: SiO2 Substrates

Cell Patterning on Photolithographically Defined Parylene-C: SiO2 Substrates

Published on: March 7, 2014

NANOPATTERNED INTERFACES FOR CONTROLLING CELL BEHAVIOR.

Kevin Chung¹, Jessica A DeQUACH¹, Karen L Christman¹

¹Department of Bioengineering, University of California, San Diego, 9500 Gilman Drive La Jolla, CA 92093-0412, USA.

|November 11, 2014

Summary

This summary is machine-generated.

This review explores how nanoscale surface patterns influence cell behavior. Understanding these interactions is key for developing new biomaterials and regenerative medicine strategies.

Keywords:

Nanopatterns cell adhesion differentiation nanotopography surface modification

More Related Videos

Expanding Nanopatterned Substrates Using Stitch Technique for Nanotopographical Modulation of Cell Behavior

Expanding Nanopatterned Substrates Using Stitch Technique for Nanotopographical Modulation of Cell Behavior

Published on: December 8, 2016

Simple, Affordable, and Modular Patterning of Cells using DNA

Simple, Affordable, and Modular Patterning of Cells using DNA

Published on: February 24, 2021

Related Experiment Videos

Last Updated: Apr 21, 2026

Cell Patterning on Photolithographically Defined Parylene-C: SiO2 Substrates

Cell Patterning on Photolithographically Defined Parylene-C: SiO2 Substrates

Published on: March 7, 2014

Expanding Nanopatterned Substrates Using Stitch Technique for Nanotopographical Modulation of Cell Behavior

Expanding Nanopatterned Substrates Using Stitch Technique for Nanotopographical Modulation of Cell Behavior

Published on: December 8, 2016

Simple, Affordable, and Modular Patterning of Cells using DNA

Simple, Affordable, and Modular Patterning of Cells using DNA

Published on: February 24, 2021

Area of Science:

Biomaterials Science
Cell Biology
Nanotechnology

Background:

Microscale surface modifications significantly impact cell functions like adhesion and differentiation.
Cellular interactions with nanoscale structures are critical as cells recognize receptors organized at this scale.
Advancements in fabrication methods, particularly from the semiconductor industry, enable nanoscale research.

Purpose of the Study:

To review cell responses to controlled topographical and biochemical cues at the nanoscale.
To identify beneficial pattern dimensions for controlling cell adhesion and differentiation.
To explore various nanoscale fabrication methods used in cell behavior studies.

Main Methods:

Review of existing literature on cell responses to nanoscale surface features.
Analysis of various nanoscale fabrication techniques (e.g., from semiconductor industry).
Examination of studies correlating pattern dimensions with cell adhesion and differentiation.

Main Results:

Nanoscale topographical and biochemical cues profoundly influence cell adhesion, proliferation, differentiation, and gene expression.
Specific pattern dimensions at the nanoscale are shown to be crucial for directing cell behavior.
Fabrication methods enable precise control over surface features for cell studies.

Conclusions:

Controlled nanoscale surface features are essential for regulating cell behavior.
Understanding nanoscale topographical and biochemical cues can guide the design of advanced biomaterials.
Further research into nanoscale fabrication and cell interactions holds promise for regenerative medicine.