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Published on: December 31, 2017
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Oral manifestation associated with avelumab
Kevin Chung1, Annu Singh2, Joseph M Huryn1
1Dental Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10065, USA.
Oral Oncology Reports
|January 19, 2026
Summary
Emerging immunotherapies like avelumab can cause side effects. This case report details a rare oral manifestation linked to avelumab treatment for cancer, including its management and resolution.
Area of Science:
- Oncology
- Immunotherapy
- Oral Medicine
Background:
- Immunotherapies are increasingly used for cancer treatment.
- Treatment toxicities can lead to debilitating systemic and oral side effects, impacting patient quality of life.
- Avelumab is an immunotherapy used for renal and metastatic urothelial carcinomas.
Purpose of the Study:
- To report a previously undescribed oral manifestation associated with avelumab therapy.
- To document the management and resolution of this oral side effect.
Main Methods:
- This is a case report.
- Clinical observation and patient history were used.
- Management strategies were implemented and monitored.
Main Results:
- An oral manifestation associated with avelumab treatment was identified.
- The specific manifestation was not previously reported in medical literature.
- Successful management led to symptom resolution.
Conclusions:
- Avelumab therapy can be associated with unique oral manifestations.
- Early recognition and management are crucial for patient well-being.
- Further research is needed to understand the incidence and mechanisms of these side effects.
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