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Updated: Apr 21, 2026

Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography
Published on: December 2, 2022
Bilateral choroidal tumors consistent with metastatic malignant paraganglioma
Thomas M Aaberg1, Erin P Benjamin, Charles V Biscotti
1*Retina Specialists of Michigan, Grand Rapids, Michigan; †Department of Neurology and Ophthalmology, Michigan State University, East Lansing, Michigan; ‡Department of Cytopathology and Clinical Pathology & Anatomic Pathology, Cleveland Clinic, Cleveland, Ohio; and §Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio.
Purpose:
To report a patient with bilateral choroidal metastasis from a malignant paraganglioma.
Methods:
Clinicopathologic case report and literature review.
Results:
A 68-year-old woman presented with bilateral amelanotic focal choroidal lesions. A thorough systemic work-up for a primary cancer revealed a paraganglioma (extraadrenal pheochromocytoma) and a pheochromocytoma of the left adrenal gland. Fine-needle aspiration biopsy of the choroidal lesion was consistent with metastatic paraganglioma.
Conclusion:
Metastatic paraganglioma, although rare, has the ability to metastasize to the choroid.

