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Updated: Apr 21, 2026
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In Vivo Multimodal Imaging and Analysis of Mouse Laser-Induced Choroidal Neovascularization Model
Published on: January 21, 2018
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Navigated laser (navilas) therapy for choroidal neovascular and hyperpermeability pathologies
Saeed T Alshahrani1, Nicola G Ghazi
1*Vitreoretinal Division, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia; †King Fahad Specialist Hospital, Dammam, Saudi Arabia; and ‡Department of Ophthalmology, University of Virginia, Charlottesville, Virginia.
Retinal Cases & Brief Reports
|November 11, 2014
Summary
Navigated laser (NAVILAS) effectively treated choroidal vascular pathologies, resolving symptoms in both central serous chorioretinopathy and choroidal neovascular membrane cases after one session.
Area of Science:
- Ophthalmology
- Medical Technology
Background:
- Central serous chorioretinopathy (CSC) and choroidal neovascularization (CNV) are significant causes of vision impairment.
- Accurate targeting of choroidal vascular lesions is crucial for effective treatment.
Observation:
- This study evaluated the navigated laser (NAVILAS) system in two patients with distinct choroidal vascular pathologies.
- One patient presented with CSC exhibiting active leakage, while the other had CNV with a discernible feeder vessel.
Findings:
- Both patients achieved successful clinical outcomes following a single NAVILAS treatment session.
- Complete resolution of subretinal fluid and leakage in CSC, and regression of subretinal blood and feeder vessel in CNV were observed.
Implications:
- NAVILAS demonstrates potential as a precise tool for treating various choroidal vascular pathologies.
- This technology may offer a minimally invasive and effective therapeutic option for retinal vascular diseases.
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